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In the body, creatine is synthesized from the amino acids glycine, arginine and methionine. Taking supplemental doses of creatine monohydrate can increase muscle creatine and phosphocreatine (PC) concentrations by up to 40%. These increases can lead to improvements in muscle energy production and recuperation. Muscle PC is used as a high-energy substrate (fuel) required for immediate bursts of energy during high intensity and anaerobic exercise. Body builders and athletes often notice remarkable increases in muscle cell size and strength, with decreases in the onset of fatigue and faster recovery.
